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Treatment of anal fissure with nitroglycerin

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Documented to be the best non-surgical option for prevention and healing of anal fissures. Previous reports have suggested initial efficacy in the treatment of anal fissures. The aim of this study was to assess the longer-term usefulness of this treatment. Methods thirty-three patients with an anal fissure were treated with topical 0. 3 nitroglycerin ointment, applied to the anoderm three times per day and after bowel movements. Topical nitroglycerin (ntg), a nitric oxide donor compound, has been shown to cause relaxation of the anal sphincter and may have treatment efficacy in the management of anal fissure. User reviews for nitroglycerin to treat anal fissure and fistula. These may include a medicated cream (to help heal the fissure), a topical muscle relaxant (to relax the anal muscles), an anesthetic ointment (to reduce pain, if pain interferes with having a bowel movement), or nitroglycerin or calcium channel blocker ointments (to relax the anal muscles and increase blood flow to the region, promoting healing). The goal of treatment is to relieve pain and discomfort, and heal the torn lining. Acute anal fissures -- the ones that dont last longer than 6 weeks -- are common and usually heal on their own.   treatment of benign anal disease with topical nitroglycerin. Author information (1)mount sinai school of medicine, new york, new york, usa. Purpose fissure-in-ano and acutely thrombosed external hemorrhoids are common, benign anal conditions, usually characterized by severe anal pain.   anal fissure is a painful condition that is caused by anodermal tearing after the passage of hard stool. Severe cases result in involuntary internal anal sphincter spasm and have traditionally been treated surgically with a lateral sphincterotomy. Investigators have demonstrated that nitric oxide causes relaxation of the smooth muscle of the anal canal, so topical nitroglycerin ointment.   acute anal fissure as a common disease in society has several etiologies and manifestations such as severe anal pain and bleeding. Documented to be the best non-surgical option for prevention and healing of anal fissures.

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